High Level Autoreactive IgE Serves as an Important Indicator in Lupus Nephritis
نویسندگان
چکیده
منابع مشابه
The prognosis of lupus nephritis in children
Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors. Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients’ outcomes and related factors were analyzed. Patient and renal survival rate were ca...
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Circular RNAs (circRNAs) participate in the pathogenesis of various diseases by sponging microRNAs (miRs). However, the roles of circRNAs remain unreported in glomerular diseases. We previously reported that miR-150 positively correlated with renal chronicity index in patients with lupus nephritis (LN). We aimed to investigate renal circRNA profiling and the interaction between circRNAs and miR...
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Systemic lupus erythematosus (SLE) is a heterogeneous disease that can affect multiple organs. A hallmark of this disease, as is the case for other autoimmune diseases, is the presence of large numbers of autoantibodies. As such, SLE is considered to be a B-cell disease perpetuated by the expansion of autoreactive T and B cells. The T cells involved have long been considered to be T-helper type...
متن کاملChemokines in lupus nephritis.
Lupus nephritis is a common solid organ manifestation of systemic lupus erythematosus (SLE). The disease is tightly linked to the production of autoantibodies and circulating immune complexes, i.e. immune complex glomerulonephritis. In this process chemokines mediate multiple biological effects, e.g. orchestrating proinflammatory microenvironments, the recruitment of immune cell subsets into th...
متن کاملLupus nephritis in children.
OBJECTIVE To determine the clinicopathological pattern of lupus nephritis in paediatric nephrology patients. DESIGN Case series study. PLACE AND DURATION OF STUDY The department of paediatric nephrology at the Children's Hospital and Institute of Child Health, Lahore, Pakistan, over a period of five years from January 2001 to December 2005. PATIENTS AND METHODS Twenty six patients upto th...
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ژورنال
عنوان ژورنال: Hong Kong Journal of Nephrology
سال: 2015
ISSN: 1561-5413
DOI: 10.1016/j.hkjn.2015.08.149